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Crockpot Mississippi Meatloaf Recipe

4.7 from 112 reviews

A flavorful and easy-to-make Crockpot Mississippi Meatloaf featuring ground beef mixed with ranch and au jus seasoning, slow-cooked to perfection with tangy pepperoncini peppers for a juicy, tender result. Perfect for a comforting weeknight dinner served over mashed potatoes or rice.

Ingredients

Scale

Meatloaf Mixture

  • 2 pounds ground beef (90/10)
  • 1 cup panko bread crumbs
  • 1 cup milk
  • 2 eggs
  • 2 (1 ounce) ranch dressing seasoning packets, divided
  • 2 (1 ounce) au jus gravy mix packets, divided
  • 1 tablespoon minced dried onion

Slow Cooker Mixture

  • 2 cups water
  • 68 pepperoncini peppers
  • Cooking spray (for greasing foil)

Optional Garnish

  • 1 tablespoon chopped fresh parsley

Instructions

  1. Prepare the Meatloaf Mixture: In a large bowl, combine the ground beef, panko bread crumbs, milk, eggs, 1 packet of ranch seasoning, 1 packet of au jus gravy mix, and minced dried onion. Mix gently until just combined to avoid tough meatloaf.
  2. Mix the Cooking Liquid: In a separate bowl, whisk together the remaining ranch packet, au jus gravy mix packet, and 2 cups of water. Set this mixture aside.
  3. Prepare the Slow Cooker: Line the bottom of a 5-quart or larger slow cooker with foil. Spray the foil generously with cooking spray to prevent sticking.
  4. Shape and Place Meatloaf: Form the meat mixture into a loaf shape and place it on the foil inside the slow cooker.
  5. Add Liquids and Peppers: Pour the water mixture over and around the meatloaf in the slow cooker. Add 6 to 8 pepperoncini peppers around the meatloaf for flavor and moisture.
  6. Cook the Meatloaf: Cover the slow cooker and cook on low for 6 hours, or on high for 3 to 4 hours, until the meatloaf is thoroughly cooked and reaches an internal temperature of 165°F (74°C).
  7. Garnish and Serve: Optionally garnish the meatloaf with chopped fresh parsley. Serve warm, ideally over mashed potatoes or rice for a hearty meal.

Notes

  • Using panko breadcrumbs gives a lighter texture than regular breadcrumbs.
  • Cooking times may vary depending on your slow cooker model; always check internal temperature.
  • Adjust the number of pepperoncini peppers for more or less tangy heat according to your taste.
  • For a lower fat option, use leaner ground beef or substitute part of the beef with ground turkey.
  • Leftovers can be stored in an airtight container in the fridge for up to 3 days or frozen for up to 3 months.

Keywords: Mississippi meatloaf, crockpot meatloaf, slow cooker dinner, easy meatloaf recipe, pepperoncini meatloaf